6545XT AdvanceBio LC/Q-TOF

Product Information

The Agilent 6545XT AdvanceBio LC/Q-TOF system is designed to handle multiple workflows in biopharmaceutical characterization. When you need to access the most information at the intact protein level, automatically confirm a sequence through peptide mapping, and confidently understand PTMs, Agilent provides a UHPLC Q-TOF that delivers

Accurately profile major and minor proteoforms with time-of-flight technology, offering new levels of sensitivity and clarity to intact protein mass spectrometry. Easily dig deeper into peptide digests with the Iterative MS/MS mode of operation. The 6545XT AdvanceBio Q-TOF is the analytical cornerstone in a comprehensive set of tools designed for biopharma.

More Information

  • Get up and running fast with quick-start methods that include Agilent AdvanceBio LC columns for intact protein and peptide workflows
  • Characterize both major and minor intact protein variations with an automated data workflow featuring MassHunter BioConfirm software
  • Adapt your instrument to your needs with SWARM autotune to ensure optimum performance with no manual adjustment
  • Large molecule tune option provides sub-nanogram detection levels for intact glycosylated monoclonal antibodies
  • Be sure of your results with mass accuracies within 10 ppm for glycosylated intact proteins
  • Dig deeper into your digested samples with the powerful iterative MS/MS feature
  • Maximize your uptime with a system tested to perform through thousands of protein injections without degradation of performance
  • Minimize maintenance delays with vent-free cleaning of entrance optics
  • Integration of either MOBILion Systems’ MOBIE or e-MSion’s ExD cell is supported