xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model

Product Information

Integration of the xCELLigence Real Time Cell Analyzer (RTCA) HT instrument with the BioTek BioSpa 8 automated incubator expands the screening throughput of your RTCA HT instrument to eight 384-well plates. Label-free high-throughput xCELLigence Real-Time Cell Analysis is ideal for screening viral mediated cytopathic effects (CPE), neutralizing antibodies, antibody-dependent cytotoxicity (ADCC), and compound mediated cytotoxicity.

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  • The xCELLigence RTCA HT instrument with BioTek BioSpa 8 automated incubator enables live cell analysis up to eight 384-well E-plates (a total of 3,072 wells) with non-invasive and label-free real-time impedance technology.
  • Kinetic measurement of cell health, viability, or response to treatments with high sensitivity, accuracy, and reproducibility, provides a continuous flow of real-time data. The information gained from real-time live cell analysis goes far beyond end-point measurements.
  • Automated workflow allows users to simply add cells to E-Plates 384 and begin kinetic measurements at physiological conditions.  The BioSpa8 Robotic Arm transfers E-Plate 384 from the incubator to the xCELLigence RTCA HT Station. Multiple E-Plates 384 are processed while unattended, saving time in the lab.
  • Critical physiological conditions are controlled and maintained in the BioSpa8 incubator to ensure assay success. Temperature and CO2/O2 control, plus humidity monitoring in the BioSpa facilitate live cell processes, and the cradle of the RTCA HT unit is temperature-controlled, for minimal disruption of the cells. The software continuously records environmental conditions.
  • Small footprint saves benchtop space
  • User-friendly RTCA software Pro HT-BioSpa enables simple assay setup (scheduling) for both single and multiple users, real-time data visualization, and powerful data analysis.
  • Ideal for high throughput screening of therapeutic antibodies, drug compounds, and cytotoxicity.
  • Typical applications include Compound-mediated cytotoxicity assay; Viral-mediated cytopathic effect (CPE); Neutralizing antibody screening; Antiviral drug screening; Immune cell potency assay; Antibody-dependent cell-mediated cytotoxicity (ADCC) assays.
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At Pegasus, we’re committed to advancing scientific progress by equipping our clients with reliable instruments and expert support, helping them to drive innovation and achieve excellence in their fields.

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